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» Physics-based simulation of biological structures
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BMCBI
2004
124views more  BMCBI 2004»
13 years 7 months ago
The Molecular Pages of the mesotelencephalic dopamine consortium (DopaNet)
Background: DopaNet http://www.dopanet.org is a Systems Biology initiative that aims to investigate precisely and quantitatively all the aspects of neurotransmission in a specific...
Nicolas Le Novère, Marco Donizelli
BMCBI
2006
155views more  BMCBI 2006»
13 years 7 months ago
CAVER: a new tool to explore routes from protein clefts, pockets and cavities
Background: The main aim of this study was to develop and implement an algorithm for the rapid, accurate and automated identification of paths leading from buried protein clefts, ...
Martin Petrek, Michal Otyepka, Pavel Banás,...
BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
Docking protein domains in contact space
Background: Many biological processes involve the physical interaction between protein domains. Understanding these functional associations requires knowledge of the molecular str...
Stefano Lise, Alice Walker-Taylor, David T. Jones
BMCBI
2006
239views more  BMCBI 2006»
13 years 7 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2007
95views more  BMCBI 2007»
13 years 7 months ago
Methods for estimating human endogenous retrovirus activities from EST databases
Background: Human endogenous retroviruses (HERVs) are surviving traces of ancient retrovirus infections and now reside within the human DNA. Recently HERV expression has been dete...
Merja Oja, Jaakko Peltonen, Jonas Blomberg, Samuel...