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» Polymorphic variants in Haskell
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BMCBI
2011
13 years 3 months ago
Pathway-based analysis using reduced gene subsets in genome-wide association studies
Background: Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to s...
Jingyuan Zhao, Simone Gupta, Mark Seielstad, Jianj...
BMCBI
2011
13 years 5 days ago
A fast and accurate method to detect allelic genomic imbalances underlying mosaic rearrangements using SNP array data
Background: Mosaicism for copy number and copy neutral chromosomal rearrangements has been recently identified as a relatively common source of genetic variation in the normal pop...
Juan R. González, Benjamin Rodriguez-Santia...
BMCBI
2007
163views more  BMCBI 2007»
13 years 8 months ago
Strainer: software for analysis of population variation in community genomic datasets
Background: Metagenomic analyses of microbial communities that are comprehensive enough to provide multiple samples of most loci in the genomes of the dominant organism types will...
John M. Eppley, Gene W. Tyson, Wayne M. Getz, Jill...
BMCBI
2007
145views more  BMCBI 2007»
13 years 8 months ago
Genome bioinformatic analysis of nonsynonymous SNPs
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...
POPL
2010
ACM
14 years 6 months ago
Static Determination of Quantitative Resource Usage for Higher-Order Programs
We describe a new automatic static analysis for determining upper-bound functions on the use of quantitative resources for strict, higher-order, polymorphic, recursive programs de...
Steffen Jost, Hans-Wolfgang Loidl, Kevin Hammond, ...