1614 search results - page 243 / 323 » Polymorphism and Genetic Programming |
BMCBI
2010
13 years 11 months ago
2010
Background: Despite the recent success of genome-wide association studies in identifying novel loci contributing effects to complex human traits, such as type 2 diabetes and obesi...
BMCBI
2010
13 years 11 months ago
2010
Background: Both somatic copy number alterations (CNAs) and germline copy number variants (CNVs) that are prevalent in healthy individuals can appear as recurrent changes in compa...
BMCBI
2008
13 years 11 months ago
2008
Background: Single nucleotide polymorphisms (SNPs) are the most common genetic variations in the human genome and are useful as genomic markers. Oligonucleotide SNP microarrays ha...
BMCBI
2007
13 years 11 months ago
2007
Background: Detection of adaptive amino acid changes in proteins under recent short-term selection is of great interest for researchers studying microevolutionary processes in mic...
BMCBI
2007
13 years 11 months ago
2007
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...