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BMCBI
2008
13 years 9 months ago
2008
Background: Genomic islands (GIs) are clusters of genes in prokaryotic genomes of probable horizontal origin. GIs are disproportionately associated with microbial adaptations of m...
BMCBI
2010
13 years 9 months ago
2010
Background: Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-ba...
BMCBI
2008
2008
Modifying the DPClus algorithm for identifying protein complexes based on new topological structures
13 years 9 months ago
Background: Identification of protein complexes is crucial for understanding principles of cellular organization and functions. As the size of protein-protein interaction set incr...
BMCBI
2008
13 years 9 months ago
2008
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
BMCBI
2007
13 years 9 months ago
2007
Background: During generation of microarray data, various forms of systematic biases are frequently introduced which limits accuracy and precision of the results. In order to prop...