Background: The study of biological systems demands computational support. If targeting a biological problem, the reuse of existing computational models can save time and effort. ...
Ron Henkel, Lukas Endler, Andre Peters, Nicolas Le...
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
Background: It has been repeatedly observed that gene order is rapidly lost in prokaryotic genomes. However, persistent synteny blocks are found when comparing more or less distan...
We study the complexity and the I/O-efficient computation of flow on triangulated terrains. We present an acyclic graph, the descent graph, that enables us to trace flow paths in ...
Mark de Berg, Otfried Cheong, Herman J. Haverkort,...
: In recent years, as a knowledge-based discipline, bioinformatics has moved to make its knowledge more computationally amenable. After its beginnings in the disciplines as a techn...