Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...
This paper focuses on parallel query optimization. We consider the operator problem and introduce a new class of execution strategies called Linear-Oriented Bushy Trees (LBTs). Co...
Background: We developed an extendable open-source Loop-mediated isothermal AMPlification (LAMP) signature design program called LAVA (LAMP Assay Versatile Analysis). LAVA was cre...
Clinton Torres, Elizabeth A. Vitalis, Brian R. Bak...
Simulated annealing (SA) and deterministic continuation are well-known generic approaches to global optimization. Deterministic continuation is computationally attractive but produ...
Background: High quality multiple alignments are crucial in the transfer of annotation from one genome to another. Multiple alignment methods strive to achieve ever increasing lev...