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BMCBI
2005
87views more  BMCBI 2005»
13 years 8 months ago
ProfNet, a method to derive profile-profile alignment scoring functions that improves the alignments of distantly related protei
Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...
Tomas Ohlson, Arne Elofsson
FGCS
2000
81views more  FGCS 2000»
13 years 8 months ago
Managing the operator ordering problem in parallel databases
This paper focuses on parallel query optimization. We consider the operator problem and introduce a new class of execution strategies called Linear-Oriented Bushy Trees (LBTs). Co...
Harald Kosch
BMCBI
2011
13 years 1 days ago
LAVA: An Open-Source Approach To Designing LAMP (Loop-Mediated Isothermal Amplification) DNA Signatures
Background: We developed an extendable open-source Loop-mediated isothermal AMPlification (LAMP) signature design program called LAVA (LAMP Assay Versatile Analysis). LAVA was cre...
Clinton Torres, Elizabeth A. Vitalis, Brian R. Bak...
SIAMIS
2010
141views more  SIAMIS 2010»
13 years 3 months ago
Optimization by Stochastic Continuation
Simulated annealing (SA) and deterministic continuation are well-known generic approaches to global optimization. Deterministic continuation is computationally attractive but produ...
Marc C. Robini, Isabelle E. Magnin
BMCBI
2007
135views more  BMCBI 2007»
13 years 8 months ago
Automatic extraction of reliable regions from multiple sequence alignments
Background: High quality multiple alignments are crucial in the transfer of annotation from one genome to another. Multiple alignment methods strive to achieve ever increasing lev...
Timo Lassmann, Erik L. L. Sonnhammer