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BMCBI
2008
57views more  BMCBI 2008»
13 years 11 months ago
Precise detection of rearrangement breakpoints in mammalian chromosomes
Claire Lemaitre, Eric Tannier, Christian Gautier, ...
RECOMB
2003
Springer
14 years 11 months ago
Transforming men into mice: the Nadeau-Taylor chromosomal breakage model revisited
Although analysis of genome rearrangements was pioneered by Dobzhansky and Sturtevant 65 years ago, we still know very little about the rearrangement events that produced the exis...
Pavel A. Pevzner, Glenn Tesler
JCB
2008
144views more  JCB 2008»
13 years 11 months ago
Multi-Break Rearrangements and Breakpoint Re-Uses: From Circular to Linear Genomes
Multi-break rearrangements break a genome into multiple fragments and further glue them together in a new order. While 2-break rearrangements represent standard reversals, fusions...
Max A. Alekseyev
RECOMB
2004
Springer
14 years 11 months ago
Chromosomal breakpoint re-use in the inference of genome sequence rearrangement
In order to apply gene-order rearrangement algorithms to the comparison of genome sequences, Pevzner and Tesler [9] bypass gene finding and ortholog identification, and use the or...
David Sankoff, Phil Trinh
RECOMB
2010
Springer
13 years 9 months ago
Limited Lifespan of Fragile Regions in Mammalian Evolution
An important question in genome evolution is whether there exist fragile regions (rearrangement hotspots) where chromosomal rearrangements are happening over and over again. Althou...
Max A. Alekseyev, Pavel A. Pevzner