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JOT
2007
123views more  JOT 2007»
13 years 8 months ago
Towards a Tool Supporting Integration Testing of Aspect-Oriented Programs
Aspect-Oriented Programming is an emerging software engineering paradigm. It offers new constructs and tools improving separation of crosscutting concerns into single units called...
Philippe Massicotte, Linda Badri, Mourad Badri
BMCBI
2010
110views more  BMCBI 2010»
13 years 8 months ago
MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
Background: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitop...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2004
94views more  BMCBI 2004»
13 years 8 months ago
GASP: Gapped Ancestral Sequence Prediction for proteins
Background: The prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a sim...
Richard J. Edwards, Denis C. Shields
BMCBI
2011
12 years 11 months ago
In-silico prediction of disorder content using hybrid sequence representation
Background: Intrinsically disordered proteins play important roles in various cellular activities and their prevalence was implicated in a number of human diseases. The knowledge ...
Marcin J. Mizianty, Tuo Zhang, Bin Xue, Yaoqi Zhou...
RECOMB
2009
Springer
14 years 8 months ago
COE: A General Approach for Efficient Genome-Wide Two-Locus Epistasis Test in Disease Association Study
The availability of high density single nucleotide polymorphisms (SNPs) data has made genome-wide association study computationally challenging. Twolocus epistasis (gene-gene inter...
Xiang Zhang, Feng Pan, Yuying Xie, Fei Zou, Wei Wa...