Aspect-Oriented Programming is an emerging software engineering paradigm. It offers new constructs and tools improving separation of crosscutting concerns into single units called...
Background: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitop...
Background: The prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a sim...
Background: Intrinsically disordered proteins play important roles in various cellular activities and their prevalence was implicated in a number of human diseases. The knowledge ...
Marcin J. Mizianty, Tuo Zhang, Bin Xue, Yaoqi Zhou...
The availability of high density single nucleotide polymorphisms (SNPs) data has made genome-wide association study computationally challenging. Twolocus epistasis (gene-gene inter...