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BMCBI
2007
99views more  BMCBI 2007»
13 years 7 months ago
Towards validating the hypothesis of phylogenetic profiling
Background: As the number of fully sequenced genome increases, the need is greater for bioinformatics to predict or annotate genes of a newly sequenced genome. Ever since Eisenber...
Raja Loganantharaj, Mazen Atwi
BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
CSB
2004
IEEE
106views Bioinformatics» more  CSB 2004»
13 years 11 months ago
Positive Sample Only Learning (PSOL) for Predicting RNA Genes in E. coli
RNA genes lack most of the signals used for protein gene identification. A major shortcoming of previous discriminative methods to distinguish functional RNA (fRNA) genes from oth...
Richard F. Meraz, Xiaofeng He, Chris H. Q. Ding, S...
NAR
2006
91views more  NAR 2006»
13 years 7 months ago
YOGY: a web-based, integrated database to retrieve protein orthologs and associated Gene Ontology terms
We present YOGY a web-based resource for orthologous proteins from nine eukaryotic organisms: Homo sapiens, Mus musculus, Rattus norvegicus, Arabidopsis thaliana, Drosophila melan...
Christopher J. Penkett, James A. Morris, Valerie W...