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BMCBI
2010
96views more  BMCBI 2010»
13 years 9 months ago
Incorporating gene co-expression network in identification of cancer prognosis markers
Background: Extensive biomedical studies have shown that clinical and environmental risk factors may not have sufficient predictive power for cancer prognosis. The development of ...
Shuangge Ma, Mingyu Shi, Yang Li, Danhui Yi, Ben-C...
BIOINFORMATICS
2007
161views more  BIOINFORMATICS 2007»
13 years 9 months ago
Functional evaluation of domain-domain interactions and human protein interaction networks
: Large amounts of protein and domain interaction data are being produced by experimental high-throughput techniques and computational approaches. To gain insight into the value of...
Andreas Schlicker, Carola Huthmacher, Fidel Ram&ia...
JIB
2006
102views more  JIB 2006»
13 years 8 months ago
Analysing Microarray Data using the Multi-functional Immune Ontologiser
Gene expression microarrays are a prominent experimental tool in functional genomics allowing researchers to gain a deeper understanding of biological processes. To date, no such ...
Sabah Khalid, Karl Fraser, Mohsin Khan, Ping Wang,...
BMCBI
2007
167views more  BMCBI 2007»
13 years 8 months ago
A stochastic differential equation model for transcriptional regulatory networks
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Adriana Climescu-Haulica, Michelle D. Quirk
BMCBI
2010
108views more  BMCBI 2010»
13 years 9 months ago
Comparison of scores for bimodality of gene expression distributions and genome-wide evaluation of the prognostic relevance of h
Background: A major goal of the analysis of high-dimensional RNA expression data from tumor tissue is to identify prognostic signatures for discriminating patient subgroups. For t...
Birte Hellwig, Jan G. Hengstler, Marcus Schmidt, M...