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» Predicting Nucleolar Proteins Using Support-Vector Machines
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BMCBI
2007
119views more  BMCBI 2007»
13 years 7 months ago
Efficacy of different protein descriptors in predicting protein functional families
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...
BMCBI
2006
85views more  BMCBI 2006»
13 years 7 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen
DMKD
2003
ACM
110views Data Mining» more  DMKD 2003»
14 years 20 days ago
Weave amino acid sequences for protein secondary structure prediction
Given a known protein sequence, predicting its secondary structure can help understand its three-dimensional (tertiary) structure, i.e., the folding. In this paper, we present an ...
Xiaochun Yang, Bin Wang
AI
2005
Springer
13 years 7 months ago
Fast Protein Superfamily Classification Using Principal Component Null Space Analysis
Abstract. The protein family classification problem, which consists of determining the family memberships of given unknown protein sequences, is very important for a biologist for ...
Leon French, Alioune Ngom, Luis Rueda
BMCBI
2004
133views more  BMCBI 2004»
13 years 7 months ago
Esub8: A novel tool to predict protein subcellular localizations in eukaryotic organisms
Background: Subcellular localization of a new protein sequence is very important and fruitful for understanding its function. As the number of new genomes has dramatically increas...
Qinghua Cui, Tianzi Jiang, Bing Liu, Songde Ma