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» Predicting Nucleolar Proteins Using Support-Vector Machines
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BMCBI
2006
159views more  BMCBI 2006»
13 years 9 months ago
Prediction of protein continuum secondary structure with probabilistic models based on NMR solved structures
Background: The structure of proteins may change as a result of the inherent flexibility of some protein regions. We develop and explore probabilistic machine learning methods for...
Mikael Bodén, Zheng Yuan, Timothy L. Bailey
BMCBI
2006
118views more  BMCBI 2006»
13 years 9 months ago
Predicting the effect of missense mutations on protein function: analysis with Bayesian networks
Background: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, ...
Chris J. Needham, James R. Bradford, Andrew J. Bul...
BMCBI
2007
141views more  BMCBI 2007»
13 years 9 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...
DMIN
2006
122views Data Mining» more  DMIN 2006»
13 years 11 months ago
Cost-Sensitive Analysis in Multiple Time Series Prediction
- In this paper we propose a new methodology for Cost-Benefit analysis in a multiple time series prediction problem. The proposed model is evaluated in a real world application bas...
Chamila Walgampaya, Mehmed M. Kantardzic
BMCBI
2010
150views more  BMCBI 2010»
13 years 10 months ago
Automatic structure classification of small proteins using random forest
Background: Random forest, an ensemble based supervised machine learning algorithm, is used to predict the SCOP structural classification for a target structure, based on the simi...
Pooja Jain, Jonathan D. Hirst