Recognition of a protein’s fold provides valuable information about its function. While many sequence-based homology prediction methods exist, an important challenge remains: tw...
Background: In the past decades, various protein subcellular-location (SCL) predictors have been developed. Most of these predictors, like TMHMM 2.0, SignalP 3.0, PrediSi and Phob...
Miaomiao Zhou, Jos Boekhorst, Christof Francke, Ro...
Background: The recent increase in the use of high-throughput two-hybrid analysis has generated large quantities of data on protein interactions. Specifically, the availability of...
Phenotypic differences between closely-related species may arise from differential expression regimes, rather than different gene complements. Knowledge of cellular protein levels ...
Background: Protein topology representations such as residue contact maps are an important intermediate step towards ab initio prediction of protein structure. Although improvemen...