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» Predicting Peroxisomal Proteins
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BMCBI
2008
123views more  BMCBI 2008»
13 years 8 months ago
Validation of protein models by a neural network approach
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
Paolo Mereghetti, Maria Luisa Ganadu, Elena Papale...
BMCBI
2007
216views more  BMCBI 2007»
13 years 8 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
BMCBI
2007
93views more  BMCBI 2007»
13 years 8 months ago
SVM-Fold: a tool for discriminative multi-class protein fold and superfamily recognition
Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...
Iain Melvin, Eugene Ie, Rui Kuang, Jason Weston, W...
GECCO
2008
Springer
104views Optimization» more  GECCO 2008»
13 years 9 months ago
Protein-protein functional association prediction using genetic programming
Determining if a group of proteins are functionally associated among themselves is an open problem in molecular biology. Within our long term goal of applying Genetic Programming ...
Beatriz García, Ricardo Aler, Agapito Ledez...
BMCBI
2008
97views more  BMCBI 2008»
13 years 8 months ago
SiteSeek: Post-translational modification analysis using adaptive locality-effective kernel methods and new profiles
Background: Post-translational modifications have a substantial influence on the structure and functions of protein. Post-translational phosphorylation is one of the most common m...
Paul D. Yoo, Yung Shwen Ho, Bing Bing Zhou, Albert...