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» Predicting Peroxisomal Proteins
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ISMB
1998
13 years 9 months ago
Bayesian Protein Family Classifier
A Bayesian procedure for the simultaneous alignment and classification of sequences into subclasses is described. This Gibbs sampling algorithm iterates between an alignment step ...
Kunbin Qu, Lee Ann McCue, Charles E. Lawrence
BIOINFORMATICS
2011
13 years 3 months ago
Integrative network alignment reveals large regions of global network similarity in yeast and human
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
Oleksii Kuchaiev, Natasa Przulj
BMCBI
2011
13 years 3 months ago
OrthoInspector: comprehensive orthology analysis and visual exploration
Background: The accurate determination of orthology and inparalogy relationships is essential for comparative sequence analysis, functional gene annotation and evolutionary studie...
Benjamin Linard, Julie D. Thompson, Olivier Poch, ...
EVOW
2010
Springer
14 years 2 months ago
A Local Search Appproach for Transmembrane Segment and Signal Peptide Discrimination
Discriminating between secreted and membrane proteins is a challenging task. This is particularly true for discriminating between transmembrane segments and signal peptides because...
Sami Laroum, Dominique Tessier, Béatrice Du...
GECCO
2005
Springer
119views Optimization» more  GECCO 2005»
14 years 1 months ago
A multi-objective evolutionary approach to peptide structure redesign and stabilization
The prediction of the native structures of proteins, the socalled protein folding problem, is a NP hard multi-minima optimization problem for which to date no routine solutions ex...
Tim Hohm, Daniel Hoffmann