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» Predicting Peroxisomal Proteins
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BMCBI
2007
115views more  BMCBI 2007»
13 years 8 months ago
How accurate and statistically robust are catalytic site predictions based on closeness centrality?
Background: We examine the accuracy of enzyme catalytic residue predictions from a network representation of protein structure. In this model, amino acid α-carbons specify vertic...
Eric Chea, Dennis R. Livesay
BMCBI
2006
101views more  BMCBI 2006»
13 years 8 months ago
Predicting residue contacts using pragmatic correlated mutations method: reducing the false positives
Background: Predicting residues' contacts using primary amino acid sequence alone is an important task that can guide 3D structure modeling and can verify the quality of the ...
Petras J. Kundrotas, Emil Alexov
BMCBI
2006
180views more  BMCBI 2006»
13 years 8 months ago
Building multiclass classifiers for remote homology detection and fold recognition
Motivation Protein remote homology prediction and fold recognition are central problems in computational biology. Supervised learning algorithms based on support vector machines a...
Huzefa Rangwala, George Karypis
EVOW
2009
Springer
14 years 2 days ago
A Hierarchical Classification Ant Colony Algorithm for Predicting Gene Ontology Terms
Abstract. This paper proposes a novel Ant Colony Optimisation algorithm for the hierarchical problem of predicting protein functions using the Gene Ontology (GO). The GO structure ...
Fernando E. B. Otero, Alex Alves Freitas, Colin G....
BMCBI
2010
175views more  BMCBI 2010»
13 years 8 months ago
Calibur: a tool for clustering large numbers of protein decoys
Background: Ab initio protein structure prediction methods generate numerous structural candidates, which are referred to as decoys. The decoy with the most number of neighbors of...
Shuai Cheng Li, Yen Kaow Ng