High-throughput methods can directly detect the set of interacting proteins in yeast but the results are often incomplete and exhibit high false positive and false negative rates....
Background: Metalloproteins are proteins capable of binding one or more metal ions, which may be required for their biological function, for regulation of their activities or for ...
Andrea Passerini, Claudia Andreini, Sauro Menchett...
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Background: Systematic approaches for identifying proteins involved in different types of cancer are needed. Experimental techniques such as microarrays are being used to characte...
Background: In a previous report (La et al., Proteins, 2005), we have demonstrated that the identification of phylogenetic motifs, protein sequence fragments conserving the overal...