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BMCBI
2010
88views more  BMCBI 2010»
13 years 10 months ago
Proteome scanning to predict PDZ domain interactions using support vector machines
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
Shirley Hui, Gary D. Bader
BMCBI
2007
116views more  BMCBI 2007»
13 years 10 months ago
MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes
Background: Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures pre...
Huaiqiu Zhu, Gang-Qing Hu, Yi-Fan Yang, Jin Wang, ...
BMCBI
2005
114views more  BMCBI 2005»
13 years 9 months ago
A new decoding algorithm for hidden Markov models improves the prediction of the topology of all-beta membrane proteins
Background: Structure prediction of membrane proteins is still a challenging computational problem. Hidden Markov models (HMM) have been successfully applied to the problem of pre...
Piero Fariselli, Pier Luigi Martelli, Rita Casadio
BMCBI
2004
93views more  BMCBI 2004»
13 years 9 months ago
Predicting binding sites of hydrolase-inhibitor complexes by combining several methods
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
SC
2009
ACM
14 years 4 months ago
Many task computing for multidisciplinary ocean sciences: real-time uncertainty prediction and data assimilation
Error Subspace Statistical Estimation (ESSE), an uncertainty prediction and data assimilation methodology employed for real-time ocean forecasts, is based on a characterization an...
Constantinos Evangelinos, Pierre F. J. Lermusiaux,...