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BMCBI
2006
2006
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
13 years 10 months ago
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
BMCBI
2007
13 years 10 months ago
2007
Background: Peptidases are proteolytic enzymes responsible for fundamental cellular activities in all organisms. Apparently about 2–5% of the genes encode for peptidases, irresp...
BMCBI
2004
13 years 10 months ago
2004
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
PVLDB
2008
13 years 10 months ago
2008
Time series data is common in many settings including scientific and financial applications. In these applications, the amount of data is often very large. We seek to support pred...
ISSRE
2010
IEEE
13 years 9 months ago
2010
IEEE
—Coupling in software applications is often used as an indicator of external quality attributes such as fault-proneness. In fact, the correlation of coupling metrics and faults i...