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BMCBI
2007
13 years 11 months ago
2007
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
BMCBI
2007
13 years 11 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
BMCBI
2007
13 years 11 months ago
2007
Background: A microarray study may select different differentially expressed gene sets because of different selection criteria. For example, the fold-change and p-value are two co...
BMCBI
2008
13 years 11 months ago
2008
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
BMCBI
2007
13 years 11 months ago
2007
Background: False occurrences of functional motifs in protein sequences can be considered as random events due solely to the sequence composition of a proteome. Here we use a nume...