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BMCBI
2004
96views more  BMCBI 2004»
13 years 10 months ago
A hybrid clustering approach to recognition of protein families in 114 microbial genomes
Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...
BMCBI
2004
125views more  BMCBI 2004»
13 years 10 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...
BMCBI
2004
205views more  BMCBI 2004»
13 years 10 months ago
A combinational feature selection and ensemble neural network method for classification of gene expression data
Background: Microarray experiments are becoming a powerful tool for clinical diagnosis, as they have the potential to discover gene expression patterns that are characteristic for...
Bing Liu, Qinghua Cui, Tianzi Jiang, Songde Ma
BMCBI
2004
111views more  BMCBI 2004»
13 years 10 months ago
Multiclass discovery in array data
Background: A routine goal in the analysis of microarray data is to identify genes with expression levels that correlate with known classes of experiments. In a growing number of ...
Yingchun Liu, Markus Ringnér
BMCBI
2004
151views more  BMCBI 2004»
13 years 10 months ago
A computational approach for ordering signal transduction pathway components from genomics and proteomics Data
Background: Signal transduction is one of the most important biological processes by which cells convert an external signal into a response. Novel computational approaches to mapp...
Yin Liu, Hongyu Zhao
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