Background: Selection of relevant genes for sample classification is a common task in most gene expression studies, where researchers try to identify the smallest possible set of ...
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
Fang Fang, Shicai Fan, Xuegong Zhang, Michael Q. Z...
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Motivation: direct bearing whose expres Sorlie et al., 2 gene sets is a diseases (Lossos et al., 2004; Miklos and Maleszka, 2004), and the variables that could account questions i...
Liat Ein-Dor, Itai Kela, Gad Getz, David Givol, Ey...
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...