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UM
2005
Springer
14 years 29 days ago
Modeling Individual and Collaborative Problem Solving in Medical Problem-Based Learning
Abstract. Since problem solving in group problem-based learning is a collaborative process, modeling individuals and the group is necessary if we wish to develop an intelligent tut...
Siriwan Suebnukarn, Peter Haddawy
BMCBI
2005
108views more  BMCBI 2005»
13 years 7 months ago
The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymer
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
François Ferron, Cécile Bussetta, H&...
BMCBI
2006
87views more  BMCBI 2006»
13 years 7 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
BMCBI
2008
80views more  BMCBI 2008»
13 years 7 months ago
Computational evaluation of TIS annotation for prokaryotic genomes
Background: Accurate annotation of translation initiation sites (TISs) is essential for understanding the translation initiation mechanism. However, the reliability of TIS annotat...
Gang-Qing Hu, Xiaobin Zheng, Li-Ning Ju, Huaiqiu Z...
BMCBI
2007
167views more  BMCBI 2007»
13 years 7 months ago
A stochastic differential equation model for transcriptional regulatory networks
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Adriana Climescu-Haulica, Michelle D. Quirk