A considerable fraction of yeast gene promoters are bound by multiple transcription factors. To study the combinatorial interactions of multiple transcription factors is thus impor...
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
Abstract. Recent studies demonstrating the existence of special non-coding "antisense" RNAs used in post-transcriptional gene regulation have received considerable attent...
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...