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BMCBI
2010
172views more  BMCBI 2010»
13 years 8 months ago
Comparison of evolutionary algorithms in gene regulatory network model inference
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
Alina Sîrbu, Heather J. Ruskin, Martin Crane
NAR
2010
194views more  NAR 2010»
13 years 3 months ago
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data
Alternative splicing is an important mechanism for increasing protein diversity. However, its functional effects are largely unknown. Here, we present our new software workflow co...
Dorothea Emig, Nathan Salomonis, Jan Baumbach, Tho...
BMCBI
2004
151views more  BMCBI 2004»
13 years 8 months ago
A computational approach for ordering signal transduction pathway components from genomics and proteomics Data
Background: Signal transduction is one of the most important biological processes by which cells convert an external signal into a response. Novel computational approaches to mapp...
Yin Liu, Hongyu Zhao
BMCBI
2006
157views more  BMCBI 2006»
13 years 8 months ago
Comparison of protein interaction networks reveals species conservation and divergence
Background: Recent progresses in high-throughput proteomics have provided us with a first chance to characterize protein interaction networks (PINs), but also raised new challenge...
Zhi Liang, Meng Xu, Maikun Teng, Liwen Niu
BIB
2008
74views more  BIB 2008»
13 years 8 months ago
The relative value of operon predictions
For most organisms, computational operon predictions are the only source of genome-wide operon information. Operon prediction methods described in literature are based on (a combi...
Rutger W. W. Brouwer, Oscar P. Kuipers, Sacha A. F...