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CSB
2005
IEEE
137views Bioinformatics» more  CSB 2005»
14 years 2 months ago
Improving Operon Prediction in E. coli
In bacterium, genes working in the same pathway or interacting with each other are often organized into operons. Currently, the prediction accuracy for operon/boundary gene pairs ...
PhuongAn Dam, Victor Olman, Ying Xu
BMCBI
2005
178views more  BMCBI 2005»
13 years 8 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
IJCNN
2008
IEEE
14 years 2 months ago
Dataset complexity can help to generate accurate ensembles of k-nearest neighbors
— Gene expression based cancer classification using classifier ensembles is the main focus of this work. A new ensemble method is proposed that combines predictions of a small ...
Oleg Okun, Giorgio Valentini
BMCBI
2007
122views more  BMCBI 2007»
13 years 8 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2008
135views more  BMCBI 2008»
13 years 8 months ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...