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IJCAI
2007
13 years 10 months ago
Integration of Hybrid Bio-Ontologies using Bayesian Networks for Knowledge Discovery
This paper describes how high level biological knowledge obtained from ontologies such as the Gene Ontology (GO) can be integrated with low level information extracted from a Baye...
Kenneth McGarry, Sheila Garfield, Nick Morris, Ste...
BCB
2010
127views Bioinformatics» more  BCB 2010»
13 years 3 months ago
A novel network model for molecular prognosis
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes and functional pathways in biomarker identification. This study presents a no...
Ying-Wooi Wan, Swetha Bose, James Denvir, Nancy La...
BMCBI
2004
150views more  BMCBI 2004»
13 years 8 months ago
Graph-based iterative Group Analysis enhances microarray interpretation
Background: One of the most time-consuming tasks after performing a gene expression experiment is the biological interpretation of the results by identifying physiologically impor...
Rainer Breitling, Anna Amtmann, Pawel Herzyk
BMCBI
2007
119views more  BMCBI 2007»
13 years 8 months ago
Efficacy of different protein descriptors in predicting protein functional families
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...
CSB
2005
IEEE
161views Bioinformatics» more  CSB 2005»
14 years 2 months ago
Data Integration in the Mouse Genome Informatics (MGI) Database
The Mouse Genome Informatics (MGI) Database at The Jackson Laboratory provides a comprehensive public resource about the laboratory mouse. MGI curated data types include gene repr...
Donnie Qi, Judith A. Blake, James A. Kadin, Joel E...