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BMCBI
2010
133views more  BMCBI 2010»
13 years 8 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
GECCO
2007
Springer
197views Optimization» more  GECCO 2007»
14 years 2 months ago
Computational intelligence techniques: a study of scleroderma skin disease
This paper presents an analysis of microarray gene expression data from patients with and without scleroderma skin disease using computational intelligence and visual data mining ...
Julio J. Valdés, Alan J. Barton
BMCBI
2007
151views more  BMCBI 2007»
13 years 8 months ago
The Genopolis Microarray Database
Background: Gene expression databases are key resources for microarray data management and analysis and the importance of a proper annotation of their content is well understood. ...
Andrea Splendiani, Marco Brandizi, Gael Even, Otta...
BMCBI
2007
107views more  BMCBI 2007»
13 years 8 months ago
A computational approach for detecting peptidases and their specific inhibitors at the genome level
Background: Peptidases are proteolytic enzymes responsible for fundamental cellular activities in all organisms. Apparently about 2–5% of the genes encode for peptidases, irresp...
Lisa Bartoli, Remo Calabrese, Piero Fariselli, Dam...
BIOCOMP
2007
13 years 10 months ago
Prediction of trans-antisense Transcripts in Arabidopsis thaliana
Background: Natural antisense transcripts (NATs) are coding or non-coding RNAs with sequence complementarity to other transcripts (sense transcripts). These RNAs could potentially...
Huan Wang, Nam-Hai Chua, Xiu-Jie Wang