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BMCBI
2004
144views more  BMCBI 2004»
13 years 8 months ago
GOtcha: a new method for prediction of protein function assessed by the annotation of seven genomes
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
BIBE
2004
IEEE
179views Bioinformatics» more  BIBE 2004»
14 years 9 days ago
Incorporating Ontology-Driven Similarity Knowledge into Functional Genomics: An Exploratory Study
This research explores the feasibility of semantic similarity approaches to supporting predictive tasks in functional genomics. It aims to establish potential relationships betwee...
Francisco Azuaje, Olivier Bodenreider
BMCBI
2006
174views more  BMCBI 2006»
13 years 8 months ago
Genome wide prediction of protein function via a generic knowledge discovery approach based on evidence integration
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
Jianghui Xiong, Simon Rayner, Kunyi Luo, Yinghui L...
BMCBI
2008
170views more  BMCBI 2008»
13 years 8 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou
BMCBI
2006
156views more  BMCBI 2006»
13 years 8 months ago
GOFFA: Gene Ontology For Functional Analysis - A FDA Gene Ontology Tool for Analysis of Genomic and Proteomic Data
Background: Gene Ontology (GO) characterizes and categorizes the functions of genes and their products according to biological processes, molecular functions and cellular componen...
Hongmei Sun, Hong Fang, Tao Chen, Roger Perkins, W...