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BIBM
2009
IEEE
192views Bioinformatics» more  BIBM 2009»
14 years 2 months ago
A Multi-task Feature Selection Filter for Microarray Classification
A major challenge in microarray classification and biomarker discovery is dealing with small-sample high-dimensional data where the number of genes used as features is typically o...
Liang Lan, Slobodan Vucetic
IEAAIE
2010
Springer
13 years 5 months ago
Constructive Neural Networks to Predict Breast Cancer Outcome by Using Gene Expression Profiles
Abstract. Gene expression profiling strategies have attracted considerable interest from biologist due to the potential for high throughput analysis of hundreds of thousands of gen...
Daniel Urda, José Luis Subirats, Leonardo F...
JCB
2007
130views more  JCB 2007»
13 years 7 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
BMCBI
2006
119views more  BMCBI 2006»
13 years 7 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
BMCBI
2010
132views more  BMCBI 2010»
13 years 7 months ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...