Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...
Iain Melvin, Eugene Ie, Rui Kuang, Jason Weston, W...
Protein fold recognition is an important step towards understanding protein three-dimensional structures and their functions. A conditional graphical model, i.e., segmentation con...
Yan Liu 0002, Jaime G. Carbonell, Peter Weigele, V...
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
We develop a novel multi-class classification method based on output codes for the problem of classifying a sequence of amino acids into one of many known protein structural class...
Eugene Ie, Jason Weston, William Stafford Noble, C...
Background: Contact order is a topological descriptor that has been shown to be correlated with several interesting protein properties such as protein folding rates and protein tr...
Yi Shi, Jianjun Zhou, David Arndt, David S. Wishar...