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» Predicting protein folding pathways
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BMCBI
2008
154views more  BMCBI 2008»
13 years 9 months ago
Sequence based residue depth prediction using evolutionary information and predicted secondary structure
Background: Residue depth allows determining how deeply a given residue is buried, in contrast to the solvent accessibility that differentiates between buried and solvent-exposed ...
Hua Zhang, Tuo Zhang, Ke Chen 0003, Shiyi Shen, Ji...
CSB
2004
IEEE
177views Bioinformatics» more  CSB 2004»
14 years 24 days ago
High-Throughput 3D Structural Homology Detection via NMR Resonance Assignment
One goal of the structural genomics initiative is the identification of new protein folds. Sequence-based structural homology prediction methods are an important means for priorit...
Christopher James Langmead, Bruce Randall Donald
BMCBI
2007
106views more  BMCBI 2007»
13 years 9 months ago
Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive as
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
Raja Jothi, Teresa M. Przytycka, L. Aravind
BMCBI
2006
169views more  BMCBI 2006»
13 years 9 months ago
Assessing protein similarity with Gene Ontology and its use in subnuclear localization prediction
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Zhengdeng Lei, Yang Dai
GCB
2003
Springer
164views Biometrics» more  GCB 2003»
14 years 2 months ago
Integrative machine learning approach for multi-class SCOP protein fold classification
: Classification and prediction of protein structure has been a central research theme in structural bioinformatics. Due to the imbalanced distribution of proteins over multi SCOP ...
Aik Choon Tan, David Gilbert, Yves Deville