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» Predicting protein functions with message passing algorithms
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141
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BMCBI
2008
128views more  BMCBI 2008»
15 years 3 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
BMCBI
2010
102views more  BMCBI 2010»
14 years 10 months ago
Predicting protein-protein interactions in unbalanced data using the primary structure of proteins
Background: Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles ...
Chi-Yuan Yu, Lih-Ching Chou, Darby Tien-Hao Chang
156
Voted
TCAD
2010
133views more  TCAD 2010»
14 years 10 months ago
Defect-Tolerant Design and Optimization of a Digital Microfluidic Biochip for Protein Crystallization
Protein crystallization is a commonly used technique for protein analysis and subsequent drug design. It predicts the 3-D arrangement of the constituent amino acids, which in turn ...
Tao Xu, Krishnendu Chakrabarty, Vamsee K. Pamula
NAR
2011
225views Computer Vision» more  NAR 2011»
14 years 6 months ago
IsoBase: a database of functionally related proteins across PPI networks
We describe IsoBase, a database identifying functionally related proteins, across five major eukaryotic model organisms: Saccharomyces cerevisiae, Drosophila melanogaster, Caenorh...
Daniel Park, Rohit Singh, Michael Baym, Chung-Shou...
KDD
2003
ACM
142views Data Mining» more  KDD 2003»
16 years 4 months ago
Frequent-subsequence-based prediction of outer membrane proteins
A number of medically important disease-causing bacteria (collectively called Gram-negative bacteria) are noted for the extra "outer" membrane that surrounds their cell....
Rong She, Fei Chen 0002, Ke Wang, Martin Ester, Je...