175 search results - page 28 / 35 » Predicting the Effects of Gene Deletion |
BMCBI
2010
13 years 7 months ago
2010
Background: Epistatic miniarray profiling (E-MAPs) is a high-throughput approach capable of quantifying aggravating or alleviating genetic interactions between gene pairs. The dat...
BMCBI
2007
13 years 7 months ago
2007
Background: Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur frequent...
BIOINFORMATICS
2012
11 years 9 months ago
2012
Motivation: Next-generation sequencing methods are generating increasingly massive datasets, yet still do not fully capture genetic diversity in the richest environments. To under...
BMCBI
2004
13 years 7 months ago
2004
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
BMCBI
2007
13 years 7 months ago
2007
Background: Analyzing differential-gene-expression data in the context of protein-interaction networks (PINs) yields information on the functional cellular status. PINs can be for...