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» Predicting the Effects of Gene Deletion
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BMCBI
2010
110views more  BMCBI 2010»
13 years 7 months ago
GenHtr: a tool for comparative assessment of genetic heterogeneity in microbial genomes generated by massive short-read sequenci
Background: Microevolution is the study of short-term changes of alleles within a population and their effects on the phenotype of organisms. The result of the below-species-level...
GongXin Yu
HPDC
2010
IEEE
13 years 8 months ago
Exploring the RNA folding energy landscape using scalable distributed cyberinfrastructure
The increasing significance of RNAs in transcriptional or post-transcriptional gene regulation processes has generated considerable interest towards the prediction of RNA folding ...
Joohyun Kim, Wei Huang, Sharath Maddineni, Fareed ...
BMCBI
2004
90views more  BMCBI 2004»
13 years 7 months ago
Haplotype frequency estimation error analysis in the presence of missing genotype data
Background: Increasingly researchers are turning to the use of haplotype analysis as a tool in population studies, the investigation of linkage disequilibrium, and candidate gene ...
Enda D. Kelly, Fabian Sievers, Ross McManus
TSP
2010
13 years 2 months ago
Selection policy-induced reduction mappings for Boolean networks
Developing computational models paves the way to understanding, predicting, and influencing the long-term behavior of genomic regulatory systems. However, several major challenges ...
Ivan Ivanov, Plamen Simeonov, Noushin Ghaffari, Xi...
BMCBI
2007
154views more  BMCBI 2007»
13 years 7 months ago
Classification of heterogeneous microarray data by maximum entropy kernel
Background: There is a large amount of microarray data accumulating in public databases, providing various data waiting to be analyzed jointly. Powerful kernel-based methods are c...
Wataru Fujibuchi, Tsuyoshi Kato