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» Predicting the Effects of Gene Deletion
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CIBCB
2006
IEEE
14 years 1 months ago
A Model-Free Greedy Gene Selection for Microarray Sample Class Prediction
— Microarray data analysis is notoriously challenging as it involves a huge number of genes compared to only a limited number of samples. Gene selection, to detect the most signi...
Yi Shi, Zhipeng Cai, Lizhe Xu, Wei Ren, Randy Goeb...
CSB
2004
IEEE
173views Bioinformatics» more  CSB 2004»
13 years 11 months ago
Gene Ontology Friendly Biclustering of Expression Profiles
The soundness of clustering in the analysis of gene expression profiles and gene function prediction is based on the hypothesis that genes with similar expression profiles may imp...
Jinze Liu, Wei Wang 0010, Jiong Yang
BMCBI
2008
111views more  BMCBI 2008»
13 years 7 months ago
Information-based methods for predicting gene function from systematic gene knock-downs
Background: The rapid annotation of genes on a genome-wide scale is now possible for several organisms using high-throughput RNA interference assays to knock down the expression o...
Matthew T. Weirauch, Christopher K. Wong, Alexandr...
ISMB
2004
13 years 8 months ago
Predicting gene regulation by sigma factors in Bacillus subtilis from genome-wide data
Motivation: Sigma factors regulate the expression of genes in Bacillus subtilis at the transcriptional level. First we assess the ability of currently available gene regulatory ne...
Michiel J. L. de Hoon, Yuko Makita, Seiya Imoto, K...
BMCBI
2006
72views more  BMCBI 2006»
13 years 7 months ago
Selecting effective siRNA sequences by using radial basis function network and decision tree learning
Background: Although short interfering RNA (siRNA) has been widely used for studying gene functions in mammalian cells, its gene silencing efficacy varies markedly and there are o...
Shigeru Takasaki, Yoshihiro Kawamura, Akihiko Kona...