175 search results - page 6 / 35 » Predicting the Effects of Gene Deletion |
BMCBI
2010
13 years 7 months ago
2010
Background: Both somatic copy number alterations (CNAs) and germline copy number variants (CNVs) that are prevalent in healthy individuals can appear as recurrent changes in compa...
BMCBI
2010
13 years 7 months ago
2010
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...
ICDM
2007
IEEE
14 years 1 months ago
2007
IEEE
— RNA molecules are distinguished by their sequence composition and by their three-dimensional shape, called the secondary structure. The secondary structure of a pre-mRNA sequen...
BMCBI
2006
13 years 7 months ago
2006
Background: Gene expression microarray technology permits the analysis of global gene expression profiles. The amount of sample needed limits the use of small excision biopsies an...
RECOMB
2007
Springer
14 years 7 months ago
2007
Springer
Learning the structure of a gene regulatory network from time-series gene expression data is a significant challenge. Most approaches proposed in the literature to date attempt to ...