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» Predicting the beta-helix fold from protein sequence data
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BMCBI
2008
146views more  BMCBI 2008»
13 years 7 months ago
Can molecular dynamics simulations help in discriminating correct from erroneous protein 3D models?
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
Jean-François Taly, Antoine Marin, Jean-Fra...
ICLP
2004
Springer
14 years 28 days ago
Protein Folding Simulation in CCP
A protein is identified by a finite sequence of aminoacids, each of them chosen from a set of 20 elements. The Protein Structure Prediction Problem is the problem of predicting t...
Alessandro Dal Palù, Agostino Dovier, Feder...
NIPS
2008
13 years 9 months ago
Predicting the Geometry of Metal Binding Sites from Protein Sequence
Metal binding is important for the structural and functional characterization of proteins. Previous prediction efforts have only focused on bonding state, i.e. deciding which prot...
Paolo Frasconi, Andrea Passerini
BMCBI
2008
117views more  BMCBI 2008»
13 years 7 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...
BMCBI
2005
150views more  BMCBI 2005»
13 years 7 months ago
Discover protein sequence signatures from protein-protein interaction data
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
Jianwen Fang, Ryan J. Haasl, Yinghua Dong, Gerald ...