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» Predicting the beta-helix fold from protein sequence data
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BMCBI
2007
147views more  BMCBI 2007»
13 years 7 months ago
Bias in random forest variable importance measures: Illustrations, sources and a solution
Variable importance measures for random forests have been receiving increased attention as a means of variable selection in many classification tasks in bioinformatics and relate...
Carolin Strobl, Anne-Laure Boulesteix, Achim Zeile...
DILS
2005
Springer
14 years 1 months ago
PLATCOM: Current Status and Plan for the Next Stages
We have been developing a system for comparing multiple genomes, PLATCOM, where users can choose genomes of their choice freely and perform analysis of the selected genomes with a...
Kwangmin Choi, Jeong-Hyeon Choi, Amit Saple, Zhipi...
BMCBI
2010
103views more  BMCBI 2010»
13 years 7 months ago
Nonparametric methods for the analysis of single-color pathogen microarrays
Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, an...
Omar J. Jabado, Sean Conlan, P. Lan Quan, Jeffrey ...
BMCBI
2007
148views more  BMCBI 2007»
13 years 7 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
Validation of an NSP-based (negative selection pattern) gene family identification strategy
Background: Gene family identification from ESTs can be a valuable resource for analysis of genome evolution but presents unique challenges in organisms for which the entire genom...
Ronald L. Frank, Cyriac Kandoth, Fikret Erç...