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JIB
2007
172views more  JIB 2007»
13 years 8 months ago
The ABC (Analysing Biomolecular Contacts)-database
As protein-protein interactions are one of the basic mechanisms in most cellular processes, it is desirable to understand the molecular details of protein-protein contacts and ult...
Peter Walter, Sam Ansari, Volkhard Helms
BMCBI
2010
97views more  BMCBI 2010»
13 years 8 months ago
Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear a
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
Maris Lapinsh, Jarl E. S. Wikberg
BMCBI
2005
97views more  BMCBI 2005»
13 years 8 months ago
Sequence variation in ligand binding sites in proteins
Background: The recent explosion in the availability of complete genome sequences has led to the cataloging of tens of thousands of new proteins and putative proteins. Many of the...
Thomas J. Magliery, Lynne Regan
APBC
2004
116views Bioinformatics» more  APBC 2004»
13 years 10 months ago
Structure-Function Relationship in DNA Sequence Recognition by Transcription Factors
Transcription factors play essential role in the gene regulation in higher organisms, binding to multiple target sequences and regulating multiple genes in a complex manner. In or...
Akinori Sarai, Samuel Selvaraj, M. Michael Gromiha...
FLAIRS
2008
13 years 11 months ago
Contrast Pattern Mining with Gap Constraints for Peptide Folding Prediction
1 In this paper, we propose a peptide folding prediction method which discovers contrast patterns to differentiate and predict peptide folding classes. A contrast pattern is defin...
Chinar C. Shah, Xingquan Zhu, Taghi M. Khoshgoftaa...