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BMCBI
2010
102views more  BMCBI 2010»
13 years 2 months ago
Predicting protein-protein interactions in unbalanced data using the primary structure of proteins
Background: Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles ...
Chi-Yuan Yu, Lih-Ching Chou, Darby Tien-Hao Chang
BMCBI
2010
142views more  BMCBI 2010»
13 years 7 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan
ICDM
2003
IEEE
148views Data Mining» more  ICDM 2003»
14 years 24 days ago
Inference of Protein-Protein Interactions by Unlikely Profile Pair
We note that a set of statistically “unusual” proteinprofile pairs in experimentally determined database of protein-protein interactions can typify protein-protein interaction...
Byung-Hoon Park, George Ostrouchov, Gong-Xin Yu, A...
RECOMB
2005
Springer
14 years 7 months ago
Towards an Integrated Protein-Protein Interaction Network
Abstract. Protein-protein interactions play a major role in most cellular processes. Thus, the challenge of identifying the full repertoire of interacting proteins in the cell is o...
Ariel Jaimovich, Gal Elidan, Hanah Margalit, Nir F...
BIBE
2005
IEEE
154views Bioinformatics» more  BIBE 2005»
14 years 1 months ago
Effective Pre-Processing Strategies for Functional Clustering of a Protein-Protein Interactions Network
In this article we present novel preprocessing techniques, based on topological measures of the network, to identify clusters of proteins from Protein-protein interaction (PPI) ne...
Duygu Ucar, Srinivasan Parthasarathy, Sitaram Asur...