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BMCBI
2006
133views more  BMCBI 2006»
13 years 10 months ago
Choosing negative examples for the prediction of protein-protein interactions
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Asa Ben-Hur, William Stafford Noble
ICUMT
2009
13 years 7 months ago
Two-layer network coordinate system for Internet distance prediction
Network coordinate (NC) system is an efficient and scalable system for Internet distance prediction. In this paper, we propose 3 two-layer NC systems HNPS, HBBS and HIDES derived f...
Chengbo Dong, Guodong Wang, Xuan Zhang, Beixing De...
ALMOB
2006
155views more  ALMOB 2006»
13 years 10 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
ISMB
1998
13 years 11 months ago
A Hidden Markov Model for Predicting Transmembrane Helices in Protein Sequences
A novel method to model and predict the location and orientation of alpha helices in membrane- spanning proteins is presented. It is based on a hidden Markov model (HMM) with an a...
Erik L. L. Sonnhammer, Gunnar von Heijne, Anders K...
MICRO
2006
IEEE
127views Hardware» more  MICRO 2006»
14 years 3 months ago
A Predictive Performance Model for Superscalar Processors
Designing and optimizing high performance microprocessors is an increasingly difficult task due to the size and complexity of the processor design space, high cost of detailed si...
P. J. Joseph, Kapil Vaswani, Matthew J. Thazhuthav...