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» Prediction Accuracy of Link-Quality Estimators
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BMCBI
2008
144views more  BMCBI 2008»
13 years 10 months ago
Local conservation scores without a priori assumptions on neutral substitution rates
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
Janis Dingel, Pavol Hanus, Niccolò Leonardi...
BMCBI
2008
118views more  BMCBI 2008»
13 years 10 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
WWW
2010
ACM
14 years 4 months ago
Modeling relationship strength in online social networks
Previous work analyzing social networks has mainly focused on binary friendship relations. However, in online social networks the low cost of link formation can lead to networks w...
Rongjing Xiang, Jennifer Neville, Monica Rogati
ISSS
2002
IEEE
124views Hardware» more  ISSS 2002»
14 years 2 months ago
Timing Analysis of Embedded Software for Speculative Processors
Static timing analysis of embedded software is important for systems with hard real-time constraints. To accurately estimate time bounds, it is essential to model the underlying m...
Abhik Roychoudhury, Xianfeng Li, Tulika Mitra
GCB
2010
Springer
122views Biometrics» more  GCB 2010»
13 years 7 months ago
Quantitative Comparison of Genomic-Wide Protein Domain Distributions
Abstract: Investigations into the origins and evolution of regulatory mechanisms require quantitative estimates of the abundance and co-occurrence of functional protein domains amo...
Arli A. Parikesit, Peter F. Stadler, Sonja J. Proh...