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BMCBI
2006
169views more  BMCBI 2006»
13 years 7 months ago
Assessing protein similarity with Gene Ontology and its use in subnuclear localization prediction
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Zhengdeng Lei, Yang Dai
BMCBI
2008
189views more  BMCBI 2008»
13 years 7 months ago
AnEnPi: identification and annotation of analogous enzymes
Background: Enzymes are responsible for the catalysis of the biochemical reactions in metabolic pathways. Analogous enzymes are able to catalyze the same reactions, but they prese...
Thomas D. Otto, Ana Carolina R. Guimarães, ...
BMCBI
2010
119views more  BMCBI 2010»
13 years 7 months ago
Functional classification of proteins based on projection of amino acid sequences: application for prediction of protein kinase
Background: The knowledge about proteins with specific interaction capacity to the protein partners is very important for the modeling of cell signaling networks. However, the exp...
Boris Sobolev, Dmitry Filimonov, Alexey Lagunin, A...
BMCBI
2006
125views more  BMCBI 2006»
13 years 7 months ago
Automated functional classification of experimental and predicted protein structures
Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
Kai Wang, Ram Samudrala
BMCBI
2010
138views more  BMCBI 2010»
13 years 7 months ago
Amino acid classification based spectrum kernel fusion for protein subnuclear localization
Background: Prediction of protein localization in subnuclear organelles is more challenging than general protein subcelluar localization. There are only three computational models...
Suyu Mei, Wang Fei