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BMCBI
2005
87views more  BMCBI 2005»
13 years 7 months ago
ProfNet, a method to derive profile-profile alignment scoring functions that improves the alignments of distantly related protei
Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...
Tomas Ohlson, Arne Elofsson
BMCBI
2006
103views more  BMCBI 2006»
13 years 7 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
BMCBI
2006
120views more  BMCBI 2006»
13 years 7 months ago
Classification of protein quaternary structure by functional domain composition
Background: The number and the arrangement of subunits that form a protein are referred to as quaternary structure. Quaternary structure is an important protein attribute that is ...
Xiaojing Yu, Chuan Wang, Yixue Li
BIRD
2007
Springer
117views Bioinformatics» more  BIRD 2007»
14 years 1 months ago
Enhancing Protein Disorder Detection by Refined Secondary Structure Prediction
More and more proteins have been observed to display functions through intrinsic disorder. Such structurally flexible regions are shown to play important roles in biological proces...
Chung-Tsai Su, Tong-Ming Hsu, Chien-Yu Chen, Yu-Ye...
BMCBI
2010
127views more  BMCBI 2010»
13 years 7 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...