Background: Carbohydrates are involved in a variety of fundamental biological processes and pathological situations. They therefore have a large pharmaceutical and diagnostic pote...
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
This paper discusses variable selection for medical decision making; in particular decisions regarding when to provide treatment and which treatment to provide. Current variable se...
Background: In sequence analysis the multiple alignment builds the fundament of all proceeding analyses. Errors in an alignment could strongly influence all succeeding analyses an...
An analytical model for cutting of a plate of material with a pair of scissors is presented in terms of concepts of contact and fracture mechanics. The forces of contact between t...