The prediction of protein 3D structure has become a hot research area in the post-genome era, through which people can understand a protein’s function in health and disease, exp...
Wenlong Li, Tao Wang, Eric Li, D. Baker, Li Jin, S...
Background: An important class of interaction switches for biological circuits and disease pathways are short binding motifs. However, the biological experiments to find these bin...
Soon-Heng Tan, Hugo Willy, Wing-Kin Sung, See-Kion...
Background: Several in silico methods exist that were developed to predict protein interactions from the copious amount of genomic and proteomic data. One of these methods is Doma...
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...