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» Prediction of indirect interactions in proteins
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NIPS
2004
13 years 8 months ago
Identifying Protein-Protein Interaction Sites on a Genome-Wide Scale
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
Haidong Wang, Eran Segal, Asa Ben-Hur, Daphne Koll...
NAR
2011
223views Computer Vision» more  NAR 2011»
12 years 10 months ago
KUPS: constructing datasets of interacting and non-interacting protein pairs with associated attributions
KUPS (The University of Kansas Proteomics Service) provides high-quality protein–protein interaction (PPI) data for researchers developing and evaluating computational models fo...
Xue-wen Chen, Jong Cheol Jeong, Patrick Dermyer
BMCBI
2011
12 years 11 months ago
HomPPI: A Class of Sequence Homology Based Protein-Protein Interface Prediction Methods
Background: Although homology-based methods are among the most widely used methods for predicting the structure and function of proteins, the question as to whether interface sequ...
Li C. Xue, Drena Dobbs, Vasant Honavar
BMCBI
2010
172views more  BMCBI 2010»
13 years 2 months ago
Nonparametric identification of regulatory interactions from spatial and temporal gene expression data
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Anil Aswani, Soile V. E. Keränen, James Brown...
BMCBI
2004
112views more  BMCBI 2004»
13 years 7 months ago
Predicting co-complexed protein pairs using genomic and proteomic data integration
Background: Identifying all protein-protein interactions in an organism is a major objective of proteomics. A related goal is to know which protein pairs are present in the same p...
Lan V. Zhang, Sharyl L. Wong, Oliver D. King, Fred...