346 search results - page 50 / 70 » Prediction of indirect interactions in proteins |
BMCBI
2006
13 years 7 months ago
2006
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
BMCBI
2010
13 years 7 months ago
2010
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
BMCBI
2010
13 years 7 months ago
2010
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
BMCBI
2007
13 years 7 months ago
2007
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
JIB
2007
13 years 7 months ago
2007
As protein-protein interactions are one of the basic mechanisms in most cellular processes, it is desirable to understand the molecular details of protein-protein contacts and ult...