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» Prediction of indirect interactions in proteins
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JCC
2011
154views more  JCC 2011»
12 years 10 months ago
Can we trust docking results? Evaluation of seven commonly used programs on PDBbind database
: Docking is one of the most commonly used techniques in drug design. It is used for both identifying correct poses of a ligand in the binding site of a protein as well as for the ...
Dariusz Plewczynski, Michal Lazniewski, Rafal Augu...
BMCBI
2007
113views more  BMCBI 2007»
13 years 7 months ago
Hinge Atlas: relating protein sequence to sites of structural flexibility
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...
Samuel Flores, Long J. Lu, Julie Yang, Nicholas Ca...
KDD
2003
ACM
190views Data Mining» more  KDD 2003»
14 years 7 months ago
Distance-enhanced association rules for gene expression
We introduce a novel data mining technique for the analysis of gene expression. Gene expression is the effective production of the protein that a gene encodes. We focus on the cha...
Aleksandar Icev, Carolina Ruiz, Elizabeth F. Ryder
IUI
2003
ACM
14 years 19 days ago
Towards more conversational and collaborative recommender systems
Current recommender systems, based on collaborative filtering, implement a rather limited model of interaction. These systems intelligently elicit information from a user only dur...
Giuseppe Carenini, Jocelyin Smith, David Poole
BMCBI
2010
191views more  BMCBI 2010»
13 years 2 months ago
Molecular dynamics simulation studies and in vitro site directed mutagenesis of avian beta-defensin Apl_AvBD2
Background: Defensins comprise a group of antimicrobial peptides, widely recognized as important elements of the innate immune system in both animals and plants. Cationicity, rath...
Soja Saghar Soman, Krishnankutty Chandrika Sivakum...